
However, most plants are used in combination as traditional herbal concoctions. The reported data helped to authenticate the claimed traditional use of these plants. usambarensis in the treatment of leukemia. Conclusions: The results of this study provided information related to the possible use of some Kenyam medicinal plants, and mostly S. usambarensis with IC 50 values of 9.04, 9.43 and 11.09 mg/mL, respectively. Other extracts having good activities included the extracts of the stem barks of Z. schimperiana stem bark extract displayed the highest cytotoxicity towards leukemia CCRF-CEM cells, with IC 50 values of 1.36 and 2.97 mg/mL, respectively. gilletii (extracted using 5% MeOH–H 2 O) and from the berries of Solanum aculeastrum (extracted with neat EtOH). sacleuxii (extracted with 50% CH 2 Cl 2 –MeOH), the stem bark of B. These include samples from the root bark of Erythrina sacleuxii (extracted with 50% n-hexane-CH 2 Cl 2), the leaves of Albizia gummifera, and Strychnos usambarensis, the stem bark of Zan-thoxylum gilletii, Bridelia micrantha, Croton sylvaticus, and Albizia schimperiana the root bark of Erythrina burttii and E. Results: At a single concentration of 10 μg/mL, 12 out of 145 extracts exhibited more than 50% cell inhibition. Materials and methods: Extracts from different plant parts (leaves, stems, stem bark, roots, root barks, aerial parts and whole herb) were obtained by cold percolation using different solvent systems, such as (1:1 v/v) dichloromethane (CH 2 Cl 2) and n-hexane (1), methanol (MeOH) and CH 2 Cl 2 (2) neat MeOH (3), 5% H 2 O in MeOH (4) and with ethanol (EtOH, 5) their cytotoxicities were determined using the resazurin reduction assay against CCRF-CEM cells.

Aim: The present study was aimed at investigating the cytotoxicity of a plethora of 145 plant parts from 91 medicinal plants, most of which are used in the management of cancer and related diseases by different communities in Kenya, against CCRF-CEM leukemia cell line. Recently there are recommendations that ethnopharmacological usages such as immune and skin disorders, inflammatory, infectious, parasitic and viral diseases should be taken into account when selecting plants that treat cancer.


Cancer is characterized as a condition with complex signs and symptoms. Ethnopharmacological relevance: Plants from Kenyan flora are traditionally used against many ailments, including cancer and related diseases.
